Chow Yun-Fat plays Ko Chun, an extremely talented and well known gambler. On the eve of a big confrontation with a famous Singaporean gambler, Ko walks into a trap set by Knife, an avid but a so-so gambler (Andy Lau), meant for an Indian servant. Struck on the head, Ko suffers from amnesia and regresses to a child-like state. Knife takes care of Ko and begins to exploit Ko's gambling talents.
Chow returns to play Ko Chun, a skilled gambler who now lives in retirement in France. Wu Xingguo plays an evil gangster who forces Ko out of retirement by killing his pregnant wife. Ko is forced to team up with a variety of other people to win out in the end. Wu Chien-lien plays Chow's romantic interest, Chingmy Yau plays a Taiwanese femme fatale, and Tony Leung provides much of the laughs.
Wong Jing's sequel to All for the Winner and spin-off to God of Gamblers finds Chow Sing Cho looking up to Michael "Dagger" Chan in order to become Ko Chun's next disciple, but the two must put aside their differences when they discover that a gang boss is bent on ruining the God of Gamblers' name.
After the events in God of Gamblers II, Tai-Kun who lost his ESP powers has regained the abilities again and seeks revenge against Sing, the Saint of Gamblers. When Tai-Kun, aided by his fellow disciples, exerts ESP powers under full force against Sing who is doing likewise to them, the spacetime becomes distorted and sends Tai-Kun and Sing to Shanghai in 1937. Meeting his own grandfather Chow Tai Fook and the benign millionaire Ding Lik, Sing must deal with Ding Lik's foes and the Japanese military forces, with his "mistaken" crush on one of a pair of twin sisters, find out who defeated the French "God of Gamblers", Pierre Cashon, in that era (the mysterious "Comment allez-vous"), and finally find out how to travel back to Hong Kong in 1991.
Following Ko Chun's earlier years as he battles for the position he was destined for: The God of Gamblers.
In the 1940s and 1950s, gangsters from Cleveland, Chicago, and New York claimed Newport, Kentucky as their own and turned it into America's first major gambling town.